PRAGUE MEDICAL REPORT, Vol 123 No 1 (2022), 27–34
POEMS Syndrome Diagnosis in a Patient with Mixed Polyneuropathy: Case Report
María Isabel Ocampo-Navia, María Andrea Negret Noreña, Luis Rafael Chaparro Santos, José Ricardo Morera Afanador, Ricardo Andrés Quintero Farías, José Luis Bustos Sánchez
DOI: https://doi.org/10.14712/23362936.2022.3
zveřejněno: 06. 03. 2022
Abstract
POEMS syndrome is a rare condition of paraneoplasic origin characterized by the presence of a sensorimotor polyneuropathy associated with the presence of a proliferative disorder of plasmatic monoclonal cells and overproduction of vascular endothelial growth factor. The acronym “POEMS” represents multisystem findings including polyneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder and skin changes; nevertheless, clinical presentation is heterogeneous. We describe a clinical case, the diagnostic and therapeutic approach in a patient with sensorimotor polyneuropathy in whom POEMS syndrome was diagnosed; to understand this pathology, its clinical and paraclinical manifestations in order to make a diagnosis or to avoid a delayed one and to provide an adequate treatment.
klíčová slova: Paraproteinemia; POEMS syndrome; Plasma cells; Plasmocytoma; Polyneuropathy
POEMS Syndrome Diagnosis in a Patient with Mixed Polyneuropathy: Case Report is licensed under a Creative Commons Attribution 4.0 International License.
167 x 240 mm
vychází: 4 x ročně
cena tištěného čísla: 450 Kč
ISSN: 1214-6994
E-ISSN: 2336-2936