PRAGUE MEDICAL REPORT
PRAGUE MEDICAL REPORT
Prague Medical Report je víceoborový biomedicínský časopis publikující původní recenzované vědecké články, přehledové a případové studie a krátké zprávy v angličtině. Časopis založený v roce 1885 jako Sborník lékařský vychází čtyřikrát ročně.

PRAGUE MEDICAL REPORT, Vol 123 No 1 (2022), 27–34

POEMS Syndrome Diagnosis in a Patient with Mixed Polyneuropathy: Case Report

María Isabel Ocampo-Navia, María Andrea Negret Noreña, Luis Rafael Chaparro Santos, José Ricardo Morera Afanador, Ricardo Andrés Quintero Farías, José Luis Bustos Sánchez

DOI: https://doi.org/10.14712/23362936.2022.3
zveřejněno: 06. 03. 2022

Abstract

POEMS syndrome is a rare condition of paraneoplasic origin characterized by the presence of a sensorimotor polyneuropathy associated with the presence of a proliferative disorder of plasmatic monoclonal cells and overproduction of vascular endothelial growth factor. The acronym “POEMS” represents multisystem findings including polyneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder and skin changes; nevertheless, clinical presentation is heterogeneous. We describe a clinical case, the diagnostic and therapeutic approach in a patient with sensorimotor polyneuropathy in whom POEMS syndrome was diagnosed; to understand this pathology, its clinical and paraclinical manifestations in order to make a diagnosis or to avoid a delayed one and to provide an adequate treatment.

klíčová slova: Paraproteinemia; POEMS syndrome; Plasma cells; Plasmocytoma; Polyneuropathy

Creative Commons License
POEMS Syndrome Diagnosis in a Patient with Mixed Polyneuropathy: Case Report is licensed under a Creative Commons Attribution 4.0 International License.

167 x 240 mm
vychází: 4 x ročně
cena tištěného čísla: 450 Kč
ISSN: 1214-6994
E-ISSN: 2336-2936

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