PRAGUE MEDICAL REPORT, Vol 120 No 4 (2019), 117–123
Immunolocalization of Gas7 in the Subgranular Zone of Mice Hippocampus
Udaya Kumar
DOI: https://doi.org/10.14712/23362936.2019.16
zveřejněno: 15. 01. 2020
Abstract
It is established that neural stem cells (NSC) reside in the hippocampal subgranular zone (SGZ) and contribute to neurogenesis throughout life. Although the molecular events that regulate hippocampal neural stem cell differentiation are known, the precise mechanism is undefined. Here, the role of growth arrest specific 7 (Gas7) protein in SGZ neural progenitor cell differentiation was studied. Immunoblotting and immunohistochemistry for Gas7 were performed on 12 weeks old mice hippocampus. The results displayed a strong signal for Gas7 protein in the mice hippocampal tissue and SGZ cells, therefore suggesting that Gas7 might have a role in neural progenitor cell differentiation in SGZ.
klíčová slova: Gas7; Neural progenitor cell; Differentiation; Subgranular zone
Immunolocalization of Gas7 in the Subgranular Zone of Mice Hippocampus is licensed under a Creative Commons Attribution 4.0 International License.
167 x 240 mm
vychází: 4 x ročně
cena tištěného čísla: 450 Kč
ISSN: 1214-6994
E-ISSN: 2336-2936
