Acta Universitatis Carolinae Kinanthropologica (AUC Kinanthropologica) is an international peer reviewed journal for the publication of research outcomes in the humanities, the social sciences and the natural sciences, as applied to kinathropology. It is a multidisciplinary journal accepting only original unpublished articles in English in the various sub-disciplines and related fields of kinanthropology, such as Anthropology, Anthropomotorics, Sports Pedagogy, Sociology of Sport, Philosophy of Sport, History of Sport, Physiology of Sport And Exercise, Physical Education, Applied Physical Education, Physiotherapy, Human Biomechanics, Psychology of Sport, Sports Training and Coaching, Sport Management, etc. The journal also welcomes interdisciplinary articles. The journal also includes reports of relevant activities and reviews of relevant publications.
The journal is abstracted and indexed by CNKI, DOAJ, EBSCO, ERIH PLUS, SPOLIT, SPORTDiscus, and Ulrichsweb.
AUC KINANTHROPOLOGICA, Vol 50 No 2 (2014), 41–55
The Evaluation of Changes in The Knee Meniscus in vivo at 3T MRI Scanner
Lenka Horňáková, Daniel Hadraba, Karel Jelen
DOI: https://doi.org/10.14712/23366052.2015.15
published online: 19. 08. 2015
abstract
Noninvasive imagining of the knee meniscus without the use of the contrast agents is more difficult compared to articular cartilage. Despite the lower signal intensity of the knee meniscus, MRI is considered the best non-invasive imaging method. Thanks to the lower water content in the meniscus compared to the surrounding tissues, it can be distinguished from the environment, but the determination of the boundaries is more complicated than in articular cartilage. There are many studies dealing with the MR imaging of the loaded and also unloaded knee, but they have mainly observed quantitative and geometric changes (movement or deformation of tissue), not targeted qualitative changes in the extracellular matrix (ECM). These changes can be evaluated with T2 relaxation times, which are more sensitive to the interaction of water molecules and the concentration of macromolecules and structures of the ECM, especially in the interaction based on the content, orientation and anisotropy of collagen fibers. Fluid and tissues with the higher water content level have long relaxation time T2. In the healthy meniscus these times are shorter; the reason is a highly organized structure of collagen and lower content of proteoglycans. To quantitatively detect changes, it is necessary to assure a sufficiently high resolution of images throughout choosing appropriate pulse sequences. After that, the acquired data can be processed to produce the T2 maps, to portray non-invasive collagen content, architecture of the ROI, changes in the water content (distribution of interstitial water in the solid matrix) and the spatial variation in depth. The aim of this work is firstly to introduce the meaning of T2 relaxation and methods for calculating T2 relaxation times. Further, the aim of this work is to give a brief description of the current pulse sequences used to display menisci.
keywords: segmentation; T2 relaxation time evaluating; T2 mapping
references (27)
1. Athanasiou, K. A., Sanchez-Adams, J. (2009). Engineering the Knee Meniscus (K. A. Athanasiou Ed. 1st ed.). Rice University. Morgan Claypool Publishers. CrossRef
2. Bae, W. C., Du, J., Bydder, G. M., Chung, C. B. (2010). Conventional and ultrashot time-to-echo magnetic resonance imaging of articular cartilage, meniscus, and intervertebral disk. Top Magn Reson Imaging 21(5), 275–289. CrossRef PubMed
3. Braun, H. J., Gold, G. E. (2012). Diagnosis of osteoarthritis: imaging. Bone 51(2), 278–288. CrossRef PubMed
4. Deligianni, X., Bär, P., Scheffler, K., et al. (2012). High-resolution Fourier-encoded sub-millisecond echo time muskuloskeletal imaging at 3 Tesla and 7 Tesla. Magnetic Resonance in Medicine 70(5), 1434–1439. CrossRef PubMed
5. Fieremans, E. (2009). Validation Methods for Diffusion Weighted Magnetic Resonance in Brain White Matter (Ph.D. thesis), Gent University, Belgium. Retrieved from: fieremans.diffusion-mri.com/validation-methods-diffusion-weighted-mri-brain-white-matter. PubMed
6. Fragonas, E., Mlynárik, V., Jellús, V., et al. (1998). Correlation between biochemical composition and magnetic resonance appearance of articular cartilace. Osteoarthritis and Cartilage 6(1), 24–32. CrossRef PubMed
7. Hashemi, R. H., Bradley, W. G., Lisanti, C. J. (2012). MRI: the basics. Lippincott Williams & Wilkins.
8. Hendrick, R. E. (2008). Breast MRI: Fundamentals and Technical Aspects. New York: Springer. CrossRef
9. Herynek, V. (2013). MR imaging – T1 and T2 relaxation, contrast of MR image, relaxometry. In vivo molecular and cell imaging 2013. Presentation – specialized seminar. ZRIR. IKEM Prague. PubMed
10. Chiang, S. W., Tsai, P. H., Chang, Y. C., et al. (2013). T2 Values of Posterior Horns of Knee Menisci in Asymptomatic Subjects. Plos One 8(3). CrossRef
11. Juras, V., Apprich, S., Zbyn, S., et al. (2013). Quantitative MRI analysis of menisci using biexponential T2* fitting with a variable echo time sequence. Magnetic Resonance in Medicine 71(3), 1015–1023. CrossRef PubMed
12. Li, X., Ma, B. C., Link, T., M., et al. (2007). In vivo T(1rho) and T(2) mapping of articular cartilage in osteoarthritis of the knee using 3 T MRI. Osteoarthritis and Cartilage 15(7), 789–797. CrossRef PubMed
13. Liess, C., Lüsse, S., Karger, N., et al. (2002). Detection of changes in cartilage water content using MRI T2-mapping in vivo. Osteoarthritis and Cartilage 10(12) 907–913. CrossRef
14. Malá, A. (2011). Dynamic T1 – contrast enhanced MR imaging. (Master thesis), Masarykova Univerzita, Přírodovědecká fakulta, Brno. Retrieved from: http://is.muni.cz/th/211542/prif_m/dipl_MRI_CA_Mala.pdf.
15. McWalter, E. J., Braun, H. J., Keenan, K. E., Gold, G. E. (2012). Knee. In Encyclopedia of Magnetic Resonance.
16. Nishii, T., Kuroda, K., Matsuoka, Y., et al. (2008). Change in knee cartilage T2 in response to mechanical loading. J Magn Reson Imaging 28(1), 175–180. CrossRef PubMed
17. Qian, Y., Williams, A. A., Chu, C. R., Boada, F. E. (2012). High resolution ultrashot echo time (UTE) imaging on human knee with AWSOS sequence at 3.0 T. Journal of Magnetic Resonance Imaging 35(1), 204–210. CrossRef PubMed
18. Rauscher, I., Stahl, R., Cheng, J., et al. (2008). Meniscal Measurements of T1 and T2 at MR Imaging in Healthy Subjects and Patients with Osteoarthritis. Radiology 249(2), 591–600. CrossRef PubMed
19. Stehling, C., Luke, A., Stahl, R., et al. (2011). Meniscal T1rho and T2 measures with 3.0T MRI increases directly after running a marathon. Skeleat Radiol 40(6), 725–735. CrossRef PubMed
20. Stehling, C., Souza, R. B., Hellio Le Graverand, M. P., et al. (2012). Loading of the knee during 3.0T MRI is associated with significantly increased medial meniscus extrusion in mild and moderate osteoarthiritis. European Journal of Radiology 81(8) 1839–1845. CrossRef PubMed
21. Subburaj, K., Kumar, D., Souza, R. B., et al. (2012). The acute effect of running on knee articular cartilage and meniscus magnetic resonance relaxation times in young healthy adults. The American Journal of Sports Medicine 40(9), 2134–2141. CrossRef PubMed
22. Thakkar, R. S., Subhawong, T., Carrio, J. A., Chhabra, A. (2011). Cartilage Magnetic Resonance Imaging Techniques at 3 T: Current Status and Future Directions. Topics in Magnetic Resonance Imaging 22(2), 71–81. CrossRef PubMed
23. Tintera, J. (2008). MR zobrazování s magnetickým polem 3 T: teoretické aspekty a praktická srovnání s 1,5 T. Česká Radiologie 62(3), 233–243.
24. Tsai, P. H., Chou, M. C., Lee, H. S., et al. (2009). MR T2 values of the knee menisci in the healthy young population: zonal and sex differences. Osteoarthritis and Cartilage 17(8), 988–994. CrossRef PubMed
25. Welsch, G. H., Trattnig, S., Scheffler, K., et al. (2008). Magnetization transfer contrast and T2 mapping in the evaluation of cartilage repair tissue with 3T MRI. Journal of Magnetic Resonance Imaging 28(4), 979–986. CrossRef PubMed
26. Williams, A., Qian, Y., Golla, S., Chu, C. R. (2012). UTE-T2* mapping detects sub-clinical meniscus injury after anterior cruciate ligament tear. Osteoarthritis and Cartilage 20(6), 486–494. CrossRef PubMed
27. Zarins, Z. A., Bolbos, R. I., Pialat, J. B., et al. (2010). Cartilage and meniscus assesment using T1rho and T2 measurements in healthy subjects and patients with osteoarthritis. Osteoarthritis and Cartilage 18(11), 1408–1416. CrossRef PubMed
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