PRAGUE MEDICAL REPORT, Vol 116 No 1 (2015), 40–48
Daily Profiles of Dehydroepiandrosterone and Its Hydroxylated Metabolites with Respect to Food Intake
Luboslav Stárka, Beáta Racz, Monika Šrámková, Martin Hill, Michaela Dušková
DOI: https://doi.org/10.14712/23362936.2015.44
published online: 27. 04. 2015
abstract
Eight women of reproductive age with normal body mass index were given 5 standardised meals, and their hormonal milieu was determined during the course of the day. Plasma from 12 withdrawals was analysed for dehydroepiandrosterone and its 7- and 16-hydroxylated metabolites. Overall, there was a maximum in the levels of steroid hormones in the morning, followed by decreases throughout the day. There was also an additional significant decrease found for dehydroepiandrosterone and its 7α-hydroxyderivative in association with the consumption of main meals, but not for the 7β-isomer or 16α-hydroxyderivative.
keywords: Daily profile; Dehydroepiandrosterone; 7-hydroxydehydroepiandrosterone; 16-hydroxydehydroepiandrosterone; Food intake
167 x 240 mm
periodicity: 4 x per year
print price: 450 czk
ISSN: 1214-6994
E-ISSN: 2336-2936
