Acta Medica (Hradec Králové) is an English language multidisciplinary medical journal. Acta Medica publishes reviews, original articles, brief communications, case reports, announcements, and notices. The journal was founded in 1958 under the title “A Collection of Scientific Works of the Charles University’s Faculty of Medicine in Hradec Králové”. The journal is indexed in Chemical Abstracts, CNKI, DOAJ, EBSCO, Hinari, Index Medicus, MEDLINE, Scopus, and Ulrichsweb.

ACTA MEDICA, Vol 63 No 1 (2020), 49–51

An Alternative Treatment for Vaginal Cuff Wart: a Case Report

Victoria Psomiadou, Christos Iavazzo, Athanasios Douligeris, Alexandros Fotiou, Anastasia Prodromidou, Nikolaos Blontzos, Evgenia Karavioti, George Vorgias

announced: 18. 05. 2020


Human papillomavirus (HPV) has been directly related to acuminate warts and cervical cancer, the second most common neoplasia among women. Given the lack of treatment against the virus itself, many medications have been utilised, mainly aiming in modifying the host’s immunological response. We present the case of a 54 years old postmenopausal patient with a history of vaginal cuff wart and HPV persistence that we managed in our clinic for 6 months with a mix of curcumin, aloe vera, amla and other natural ingredients. As the patient was found to be intolerant to imiquimod (one of the most common conservative methods of treatment) we attempted the use of curcumin, which was applied to the area of the wart three times per week for 6 months. Both clinical and colposcopical improvement was noted in regular clinic visits with regression of the lesion. The outcome of this case encourages our view that curcumin should be considered as a significant treatment modality against HPV infection and acuminate warts.

keywords: HPV; vaginal cuff wart; curcumin; Indian Grapefruit (AMLA); aloe vera; Docosanol; lactic acid; CM-β glucans; SiloffGyn

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ISSN: 1211-4286
E-ISSN: 1805-9694