ACTA MEDICA
ACTA MEDICA
Acta Medica (Hradec Králové) is an English language multidisciplinary medical journal. Acta Medica publishes reviews, original articles, brief communications, case reports, announcements, and notices. The journal was founded in 1958 under the title “A Collection of Scientific Works of the Charles University’s Faculty of Medicine in Hradec Králové”. The journal is indexed in Chemical Abstracts, CNKI, DOAJ, EBSCO, Hinari, Index Medicus, MEDLINE, Scopus, and Ulrichsweb.

ACTA MEDICA, Vol 56 No 1 (2013), 36–38

Efficacy of Topiramate as Add-on Therapy in Two Different Types of Progressive Myoclonic Epilepsy

Caner Feyzi Demir, Hasan Hüseyin Özdemir, Bülent Müngen

DOI: https://doi.org/10.14712/18059694.2014.37
published online: 23. 07. 2015

abstract

The present article describes two unrelated cases of progressive myoclonic epilepsy (PME) of the Lafora’s disease and Unverricht-Lundborg types who were treated with topiramate (TPM) as add-on therapy for their myoclonus. After the initiation of topiramate therapy both cases responded with marked decrease in myoclonic seizure frequency and improvement of quality of life. Topiramate appears to be a useful alternative agent in cases of PME and could be consider for adjunctive therapy.

keywords: Progressive myoclonic epilepsy; Topiramate

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Efficacy of Topiramate as Add-on Therapy in Two Different Types of Progressive Myoclonic Epilepsy is licensed under a Creative Commons Attribution 4.0 International License.

210 x 297 mm
periodicity: 4 x per year
print price: 150 czk
ISSN: 1211-4286
E-ISSN: 1805-9694

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